Imaging Center Equipment

About Our Equipment

Abberior FACILITY Line 3-D STED (STimulated Emission Depletion) Microscope​

  • Better than 20 nm lateral resolution, 50 nm axial resolution. ​
  • Compatible with fixed and live samples.​
  • FLIM (Fluorescence lifetime imaging microscopy) allows separations of multiple dyes and allows other insights into samples.​
  • Equipped with 20x, 40x, and 60x objectives.​

Purchased with New York State grant funding (Empire State Development Fund).

Zeiss LSM 980 with AiryScan 2 inverted LSM ​

  • Fast, gentle, 3-D and timelapse live-cell super-resolution confocal imaging with 100 nm lateral and 200 nm axial resolution.​
  • Temperature and CO2 incubated imaging chamber. ​
  • Inverted 3-D confocal microscopy with spectral unmixing to image and many (>8) color channels.​
  • Photoactivation, photobleaching, and other optical manipulations in live cells.​
  • Tiled imaging for high-resolution 3-D confocal imaging of tissue sections and mm-scale samples with many color channels.​
  • Equipped with 10x, 20x, 40x, 63x, and 100x objectives.​

ONI Nanoimager S SMLM

  • Super-resolution and single-molecule localization microscope (SMLM).​
  • 3-D, 3-channel single-molecule imaging -20 nm XY -60 nm Z ​
  • dSTORM, DNApaint, PALM, smTracking.​
  • Equipped with a 100x objective.

Zeiss Axio Examiner.Z1 2-photon LSM​

  • NLO LSM upright confocal microscope with a mks Spectra-Physics Insight 3 two-photon laser.​
  • Two-photon laser scanning microscope to image into thick tissue samples and live animal models.​
  • Equipped with 10x and 20x objectives.

BRUKER NanoString CosMx SMI (Spatial Multiomics Imager)

  • Highest commercial plex RNA (1,000-plex) and highest plex protein (>100-plex)​.​
  • Analyze RNA and protein with any sample type (FFPE, fresh frozen, organoid)​.​
  • High-resolution: Subcellular with 3-D resolution​.​
  • End-to-end platform with multi-site reproducibility​.​
  • Complete cloud solution: Image-share/collaborate, multi-data types, scalable computing.

Zeiss Axio Observer with Apotome 2 for SIM​

  • Widefield fluorescence microscope. ​
  • Tiled imaging for high-resolution 3-D confocal imaging of tissue sections and mm-scale samples with many color channels.​
  • Equipped with 5x, 10x, 20x, and 63x objectives.

Zeiss Axio Scan.Z1 ​

  • Automated slide scanner for tissue section imaging with brightfield (pathology stains) and immunofluorescence with automatic imaging of 100 slides at a time.​
  • Equipped with objectives for 5x, 10x, 20x, and 40x magnification

Nikon C2 confocal LSM

  • Upright confocal laser scanning microscope with AI-based super-resolution deconvolution software.​
  • Equipped with 10x, 20x, 40x, and 60x objectives.

Bio-Techne Namocell Pala Cell Sorter​

  • Low pressure, microfluidics-based cell sorter for single-cell analysis.​
  • Small footprint.​
  • Gene therapy.​
  • Single-cell transcriptomics.​
  • Cell lines, primary cells, nuclei, bacteria, yeast, virus, EVs.

Image Analysis Facilities

  • Comet ORS Dragonfly Workstations​
  • Custom Lume SMLM Software​
  • MBF Stereoinvestigator Desktop